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New rules to make us first to allow DNA embryo change?
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Author:  pcernie [ Sat Feb 15, 2014 2:15 pm ]
Post subject:  New rules to make us first to allow DNA embryo change?

Quote:
...hopes of tackling mitochondrial disease will be raised in a few weeks when the government announces regulations that will permit the use of an IVF technique that should rid affected families of the disorder. If these plans are approved by parliament, Britain will become the first nation to permit germ-line gene therapy, which will change the DNA of future generations in order to eradicate the condition.

The technique involves taking an egg with healthy mitochondria from a donor female. Its main set of nuclear genes is then scooped out and replaced with those of a woman affected by mitochondrial disease but whose basic nuclear DNA is healthy. The egg is then fertilised using her partner's sperm. In this way an embryo is created that has the central genes of the two parents but no longer carries the mutated mitochondrial DNA once carried by the mother. The technique is known as mitochondrial replacement. It has never been tried on humans, but has worked in animal studies.

Most scientists and doctors, particularly those who work with families touched by mitochondrial disease, support the introduction of the technique. However, some groups vociferously oppose its use. "The social benefits for a relatively small number of women … do not come near to justifying the potential health risks from these techniques to the child and the risks to global society that stem from human genetic engineering," said the campaign group Human Genetics Alert.

Anti-abortion groups also oppose mitochondrial replacement, while some tabloid newspapers have described the creation of embryos using the nuclear DNA of two parents and the mitochondrial DNA of a third-party donor as "three-parent babies" and have claimed that this represents a slippery slope to a "Frankenstein future".

This last claim particularly infuriates researchers. "It is wrong to say this produces three-parent babies," said Turnbull. "More than 99.9% of DNA is nuclear DNA and that will not be affected. Mitochondrial DNA accounts for around 0.1% of our total DNA. We are changing only mitochondrial DNA. We are not changing a person's hair or height or eye colour."


http://www.theguardian.com/science/2014 ... e-cure-ivf

So long as we (and more importantly the patients) are given all the facts for the future, I've no problem with it myself. In that scenario we'd be crazy not to do it IMO. We're going to have to take new techniques on a case by case basis, you can't just say we're not going to allow this or that when a technique could come along that the majority could be comfortable with. A chance to wipe out Alzheimers for a growing, ageing population for instance.

Author:  pcernie [ Thu Feb 27, 2014 2:16 pm ]
Post subject:  Re: New rules to make us first to allow DNA embryo change?

Three-person baby details announced

Quote:
How the creation of babies using sperm and eggs from three people will be regulated in the UK has been announced.

The draft rules will be reviewed as part of a public consultation and could come into force by the end of 2014.

Doctors say three-person IVF could eliminate debilitating and potentially fatal diseases that are passed from mother to child.

Opponents say it is unethical and could set the UK on a "slippery slope" to designer babies.

Using the parents' sperm and eggs plus an additional egg from a donor woman should prevent mitochondrial disease.


http://www.bbc.co.uk/news/health-26367220

We need to explore things like this, the potential rewards are too great not to.

Author:  Amnesia10 [ Thu Feb 27, 2014 4:10 pm ]
Post subject:  Re: New rules to make us first to allow DNA embryo change?

While it could be used to eradicate appalling genetic genetic diseases it will be inevitably abused. So you need to work out whether the abuses are so bad to make banning this technology worthwhile.

Author:  pcernie [ Thu Feb 27, 2014 4:43 pm ]
Post subject:  Re: New rules to make us first to allow DNA embryo change?

Amnesia10 wrote:
While it could be used to eradicate appalling genetic genetic diseases it will be inevitably abused. So you need to work out whether the abuses are so bad to make banning this technology worthwhile.


Just about anything can be abused, but this would be much more difficult. I don't see what's so unethical about it in some quarters, we've got the morning after pill, abortion and any other number of ways of 'playing God'... this as far as we can tell is beneficial for all society.

It's gonna happen anyway this sort of genetic manipulation, and we already treat any variety of ailments and diseases with drugs, so why not improve the process?

We're going to have to grasp the nettle on so many advancements in our lifetimes, and that's gonna require experimentation like anything else. With stuff that seemed outlandish even 20 years ago the microchip changed everything; climate and environmental change at every discipline and level, mapping the genome, drugs, cybernetic prosthetics and other 'augmentation' potential and realised... There's no going back now.

Author:  TheFrenchun [ Thu Feb 27, 2014 4:48 pm ]
Post subject:  Re: New rules to make us first to allow DNA embryo change?

pcernie wrote:
Amnesia10 wrote:
While it could be used to eradicate appalling genetic genetic diseases it will be inevitably abused. So you need to work out whether the abuses are so bad to make banning this technology worthwhile.



It's gonna happen anyway this sort of genetic manipulation, and we already treat any variety of ailments and diseases with drugs, so why not improve the process?

Depends what you define as a ailment or illness that needs tweaking. It could turn into eugenism once they run out of "illnesses" to cure:S.

Author:  pcernie [ Thu Feb 27, 2014 5:08 pm ]
Post subject:  Re: New rules to make us first to allow DNA embryo change?

TheFrenchun wrote:
pcernie wrote:
Amnesia10 wrote:
While it could be used to eradicate appalling genetic genetic diseases it will be inevitably abused. So you need to work out whether the abuses are so bad to make banning this technology worthwhile.



It's gonna happen anyway this sort of genetic manipulation, and we already treat any variety of ailments and diseases with drugs, so why not improve the process?

Depends what you define as a ailment or illness that needs tweaking. It could turn into eugenism once they run out of "illnesses" to cure:S.


I have more faith, which is unusual, granted :D

Really it's about how things are presented by those in charge and the media I suppose - the somewhat-bogus MMR scare, or even how nobody was too impressed by the 'snoopers' charter' and yet nobody gave a crap when it turned out GCHQ and the NSA hacked pretty much the entire internet. However it comes about, there's always a tipping point in either direction for the general public.

Author:  cloaked_wolf [ Thu Feb 27, 2014 5:24 pm ]
Post subject:  Re: New rules to make us first to allow DNA embryo change?

This is what I was alluding to in the thread on genetic predisposition to being gay in the news section. Would people want to minimise their chances of their offspring being gay?

Author:  TheFrenchun [ Thu Feb 27, 2014 5:32 pm ]
Post subject:  Re: New rules to make us first to allow DNA embryo change?

cloaked_wolf wrote:
This is what I was alluding to in the thread on genetic predisposition to being gay in the news section. Would people want to minimise their chances of their offspring being gay?


Or ginger? :lol:

Author:  pcernie [ Thu Feb 27, 2014 5:48 pm ]
Post subject:  Re: New rules to make us first to allow DNA embryo change?

TheFrenchun wrote:
cloaked_wolf wrote:
This is what I was alluding to in the thread on genetic predisposition to being gay in the news section. Would people want to minimise their chances of their offspring being gay?


Or ginger? :lol:


To my mind you could have a total ban on such endeavours before they even got started. Legislation that open-ended would never get through parliament come to think of it. Politically toxic.

Author:  Amnesia10 [ Thu Feb 27, 2014 5:56 pm ]
Post subject:  Re: New rules to make us first to allow DNA embryo change?

TheFrenchun wrote:
cloaked_wolf wrote:
This is what I was alluding to in the thread on genetic predisposition to being gay in the news section. Would people want to minimise their chances of their offspring being gay?


Or ginger? :lol:

Or scottish?

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